Jack Tuttle would start in relief of Penix with Donaven McCulley as the backup.
The Hoosiers were shut out for the first time since the 2000 season.
Every Big Ten team has featured in ABC’s Saturday Night Football except for Indiana.
Penn State has won eight straight games headed into Saturday’s matchup.
Last year, Indiana won with Michael Penix Jr.'s two point conversion in overtime.
The Nittany Lions look a little tougher than they did last year.
The two combined for just under a third of the team’s tackles.
Quarterback Michael Penix Jr. threw for 373 yards on 35 completions.
The Hoosiers threw for a season-high 373 yards on the night.
The Hoosiers are 1-2 after turnover-filled losses to two top-10 teams.
Western Kentucky has the best third-down efficiency in the nation.